Atlante
| Player | Status | Type | Out since | Expected back |
|---|
| Hardy Meza · MID | injured | Broken knee cap | 15 Jul 2026 · 63 days | Mid March 2027 |
Atlas
| Player | Status | Type | Out since | Expected back |
|---|
| Édgar Zaldívar · MID | injured | Thigh injury | 29 Aug 2026 · 18 days | Doubtful |
Atlético de San Luis
| Player | Status | Type | Out since | Expected back |
|---|
| César López · GK | injured | Cruciate ligament injury | 11 Aug 2026 · 36 days | Late April 2027 |
| Jesús Medina · FWD | injured | Knee injury | 18 Apr 2025 · 516 days | Late September 2026 |
| João Pedro · FWD | injured | Cruciate ligament injury | 9 Jul 2026 · 69 days | Mid January 2027 |
| Juanpe · DEF | injured | Knee injury | 11 Jul 2026 · 67 days | Doubtful |
Austin FC
| Player | Status | Type | Out since | Expected back |
|---|
| Myrto Uzuni · FWD | injured | Muscle injury | 5 Sept 2026 · 11 days | Early October 2026 |
CF América
| Player | Status | Type | Out since | Expected back |
|---|
| Raúl Zúñiga · FWD | injured | Knee injury | 28 Aug 2026 · 19 days | Mid October 2026 |
Charlotte FC
| Player | Status | Type | Out since | Expected back |
|---|
| Aron John · MID | injured | Shoulder injury | 22 Jul 2026 · 56 days | Early December 2026 |
| Harry Toffolo · DEF | injured | Knock | 15 Aug 2026 · 32 days | Late September 2026 |
| Nimfasha Berchimas · FWD | injured | Broken foot | 7 Aug 2026 · 40 days | Late October 2026 |
Columbus Crew
| Player | Status | Type | Out since | Expected back |
|---|
| Rudy Camacho · DEF | injured | Foot injury | 20 Aug 2026 · 27 days | Late September 2026 |
| Sékou Bangoura · MID | injured | Ankle injury | 15 Aug 2026 · 32 days | Late September 2026 |
| Wessam Abou Ali · FWD | injured | Knee injury | 18 Apr 2026 · 151 days | Late September 2026 |
FC Juárez
| Player | Status | Type | Out since | Expected back |
|---|
| Bryan Romero · DEF | injured | Knee injury | 10 Jul 2024 · 798 days | Doubtful |
| Ettson Ayón · FWD | injured | Knock | 16 Aug 2026 · 31 days | Doubtful |
| Lucas Romero · MID | injured | Cruciate ligament injury | 21 Jul 2026 · 57 days | Early April 2027 |
León
| Player | Status | Type | Out since | Expected back |
|---|
| Ángel Estrada · MID | injured | Broken leg | 31 Mar 2026 · 169 days | Doubtful |
| Edgar Guerra · FWD | injured | Thigh injury | 5 Aug 2026 · 42 days | Doubtful |
| Luis Valadez · MID | injured | Foot injury | 11 Sept 2026 · 5 days | Mid October 2026 |
New York City FC
| Player | Status | Type | Out since | Expected back |
|---|
| Arnau Farnós · FWD | injured | Leg injury | 31 Jul 2026 · 47 days | Late September 2026 |
| Drew Baiera · DEF | injured | Leg injury | 18 Apr 2026 · 151 days | Early November 2026 |
| Kai Trewin · MID | injured | Leg injury | 22 Jul 2026 · 56 days | Late September 2026 |
| Keaton Parks · MID | injured | Muscle injury | 5 Sept 2026 · 11 days | Late September 2026 |
| Maxi Moralez · MID | injured | Knock | 5 Sept 2026 · 11 days | Late September 2026 |
| Talles Magno · FWD | injured | Knock | 29 Aug 2026 · 18 days | Late September 2026 |
Orlando City
| Player | Status | Type | Out since | Expected back |
|---|
| Adrián Marin · DEF | injured | Thigh injury | 29 Aug 2026 · 18 days | Late September 2026 |
| Braian Ojeda · MID | injured | Foot injury | 15 Aug 2026 · 32 days | Late September 2026 |
Pachuca
| Player | Status | Type | Out since | Expected back |
|---|
| Alexéi Domínguez · FWD | injured | Broken foot | 9 Aug 2026 · 38 days | Mid November 2026 |
| Andrés Arroyo · FWD | injured | Foot injury | 9 Sept 2026 · 7 days | Mid October 2026 |
Portland Timbers
| Player | Status | Type | Out since | Expected back |
|---|
| Alexander Aravena · FWD | injured | Hip injury | 29 Aug 2026 · 18 days | Early October 2026 |
| Brandon Bye · DEF | injured | Leg injury | 29 Aug 2026 · 18 days | Late September 2026 |
| Juan Mosquera · DEF | injured | Foot injury | 11 Apr 2026 · 158 days | Late September 2026 |
Puebla
| Player | Status | Type | Out since | Expected back |
|---|
| Eduardo Navarro · DEF | injured | Physical discomfort | 12 Aug 2026 · 35 days | Doubtful |
Pumas
| Player | Status | Type | Out since | Expected back |
|---|
| Álvaro Angulo · DEF | injured | Knee injury | 14 Aug 2026 · 33 days | Doubtful |
| José Macías · FWD | injured | Knee injury | 9 Nov 2025 · 311 days | Late October 2026 |
| Sebastián Córdova · FWD | injured | Cruciate ligament injury | 8 Aug 2026 · 39 days | Late April 2027 |
Real Salt Lake
| Player | Status | Type | Out since | Expected back |
|---|
| Ariath Piol · FWD | injured | Achilles tendon injury | 7 Mar 2026 · 193 days | Late September 2026 |
| Griffin Dillon · MID | injured | Injured | 2 Aug 2026 · 45 days | Late October 2026 |
| Justen Glad · DEF | injured | Muscle injury | 22 Jul 2026 · 56 days | Late September 2026 |
| Stijn Spierings · MID | injured | Ankle injury | 29 Aug 2026 · 18 days | Early October 2026 |
| Zach Booth · MID | injured | Hamstring injury | 29 Aug 2026 · 18 days | Early October 2026 |
Santos Laguna
| Player | Status | Type | Out since | Expected back |
|---|
| Bruno Amione · DEF | injured | Cruciate ligament injury | 12 Jul 2026 · 66 days | Early January 2027 |
| Lucas Di Yorio · FWD | injured | Broken leg | 12 Aug 2026 · 35 days | Early January 2027 |
Tigres
| Player | Status | Type | Out since | Expected back |
|---|
| Francisco Reyes · DEF | injured | Achilles tendon injury | 2 Sept 2026 · 14 days | Early January 2027 |
| Jesús Angulo · DEF | injured | Knee injury | 12 Jul 2026 · 66 days | Mid November 2026 |
| Marcelo Flores · FWD | injured | Injured | 31 May 2026 · 108 days | Unknown |
| Marco Farfán · DEF | injured | Muscle injury | 16 Jul 2026 · 62 days | Doubtful |
| Osvaldo Rodríguez · DEF | injured | Knee injury | 7 May 2026 · 132 days | Doubtful |
| Vladimir Loroña · DEF | injured | Thigh injury | 29 Aug 2026 · 18 days | Doubtful |
Tijuana
| Player | Status | Type | Out since | Expected back |
|---|
| Elias Manoel · FWD | injured | Injured | 28 Aug 2026 · 19 days | Doubtful |
Toluca
| Player | Status | Type | Out since | Expected back |
|---|
| Érick Gutiérrez · MID | injured | Muscle injury | 22 Aug 2026 · 25 days | Doubtful |
| Iván López · DEF | injured | Injured | 21 Aug 2026 · 26 days | Unknown |
| Luis García · GK | injured | Thigh injury | 15 Aug 2026 · 32 days | Doubtful |
| Marcel Ruiz · MID | injured | Knee injury | 12 Jul 2026 · 66 days | Early November 2026 |
| Santiago Simón · DEF | injured | Calf injury | 22 Aug 2026 · 25 days | Doubtful |
Vancouver Whitecaps
| Player | Status | Type | Out since | Expected back |
|---|
| Belal Halbouni · DEF | injured | Knee injury | 28 Feb 2026 · 200 days | Unknown |
| Kenji Cabrera · FWD | injured | Foot injury | 16 Jul 2026 · 62 days | Late September 2026 |
| Kwasi Poku · FWD | injured | Hamstring injury | 1 Aug 2026 · 46 days | Late September 2026 |
| Ralph Priso · DEF | injured | Ankle injury | 29 Aug 2026 · 18 days | Early October 2026 |
| Ranko Veselinović · DEF | injured | Knee injury | 1 Aug 2026 · 46 days | Late September 2026 |
| Thomas Müller · MID | injured | Knock | 10 Sept 2026 · 6 days | Early October 2026 |
Injury type and out-since come from the daily squad feed; a blank type means the provider reported an injury without a category. Expected returns are the provider’s own wording.
Chicago Fire FC
Chivas
Cruz Azul
FC Cincinnati
FC Dallas
Inter Miami CF
Los Angeles FC
Minnesota United
Monterrey
Nashville SC
Necaxa
Philadelphia Union
Querétaro FC
San Diego FC
Seattle Sounders FC