Atlante
| Player | Status | Type | Out since | Expected back |
|---|
| Eduardo Tercero · DEF | injured | Knock | 23 Oct 2026 · 9 days | Doubtful |
| Hardy Meza · MID | injured | Broken knee cap | 15 Jul 2026 · 109 days | Mid March 2027 |
Atlas
| Player | Status | Type | Out since | Expected back |
|---|
| Duk · FWD | injured | Knee injury | 22 Sept 2026 · 40 days | Late March 2027 |
| Elías Montiel · MID | injured | Muscle injury | 26 Oct 2026 · 6 days | Mid November 2026 |
Austin FC
| Player | Status | Type | Out since | Expected back |
|---|
| Christopher Applewhite · DEF | injured | Muscle injury | 28 Oct 2026 · 4 days | Mid November 2026 |
| Ervin Torres · MID | injured | Ankle injury | 28 Oct 2026 · 4 days | Early December 2026 |
| Jon Bell · DEF | injured | Stomach injury | 24 Oct 2026 · 8 days | Early November 2026 |
CF América
| Player | Status | Type | Out since | Expected back |
|---|
| Álex Zendejas · FWD | injured | Muscle injury | 24 Oct 2026 · 8 days | Doubtful |
| Raphael Veiga · MID | injured | Shoulder injury | 23 Oct 2026 · 9 days | Late November 2026 |
| Raúl Zúñiga · FWD | injured | Knee injury | 28 Aug 2026 · 65 days | Doubtful |
Charlotte FC
| Player | Status | Type | Out since | Expected back |
|---|
| Archie Goodwin · FWD | injured | Knock | 10 Oct 2026 · 22 days | Early November 2026 |
| Aron John · MID | injured | Shoulder injury | 22 Jul 2026 · 102 days | Early December 2026 |
| Brandt Bronico · MID | injured | Knock | 24 Oct 2026 · 8 days | A few weeks |
| Nimfasha Berchimas · FWD | injured | Broken foot | 7 Aug 2026 · 86 days | Late October 2026 |
| Tim Ream · DEF | injured | Knock | 28 Oct 2026 · 4 days | Mid November 2026 |
| Will Cleary · DEF | injured | Illness | 24 Oct 2026 · 8 days | Early November 2026 |
Chicago Fire FC
| Player | Status | Type | Out since | Expected back |
|---|
| Robin Lod · MID | injured | Knock | 10 Oct 2026 · 22 days | Late October 2026 |
| Sam Rogers · DEF | injured | Muscle injury | 14 Oct 2026 · 18 days | Mid November 2026 |
Chivas
| Player | Status | Type | Out since | Expected back |
|---|
| Ángel Sepúlveda · FWD | injured | Muscle injury | 20 Oct 2026 · 12 days | Early November 2026 |
| Brian Gutiérrez · MID | injured | Physical discomfort | 20 Oct 2026 · 12 days | Doubtful |
| Luis Romo · DEF | injured | Hamstring injury | 5 Oct 2026 · 27 days | Doubtful |
Cruz Azul
| Player | Status | Type | Out since | Expected back |
|---|
| José Paradela · MID | injured | Strain injury | 11 Oct 2026 · 21 days | Doubtful |
FC Juárez
| Player | Status | Type | Out since | Expected back |
|---|
| Bryan Romero · DEF | injured | Knee injury | 10 Jul 2024 · 844 days | Doubtful |
| Ettson Ayón · FWD | injured | Knock | 16 Aug 2026 · 77 days | Doubtful |
| Jairo Torres · FWD | injured | Knock | 22 Sept 2026 · 40 days | Doubtful |
| Lucas Romero · MID | injured | Cruciate ligament injury | 21 Jul 2026 · 103 days | Early April 2027 |
León
| Player | Status | Type | Out since | Expected back |
|---|
| Ángel Estrada · MID | injured | Broken leg | 31 Mar 2026 · 215 days | Doubtful |
| Luis Valadez · MID | injured | Foot injury | 11 Sept 2026 · 51 days | Doubtful |
Minnesota United
| Player | Status | Type | Out since | Expected back |
|---|
| Peter Stroud · MID | injured | Foot injury | 1 Aug 2026 · 92 days | Early November 2026 |
| Wil Trapp · MID | injured | Concussion | 27 Oct 2026 · 5 days | Mid November 2026 |
Necaxa
| Player | Status | Type | Out since | Expected back |
|---|
| Alexis Peña · DEF | injured | Abdominal injury | 16 Oct 2026 · 16 days | Doubtful |
| Javier Ruiz · FWD | injured | Knock | 23 Oct 2026 · 9 days | Doubtful |
New York City FC
| Player | Status | Type | Out since | Expected back |
|---|
| Aiden O'Neill · MID | injured | Ankle injury | 31 Oct 2026 · 1 day | Doubtful |
| Alonso Martínez · FWD | injured | Muscle injury | 29 Oct 2026 · 3 days | A few weeks |
| Arnau Farnós · FWD | injured | Leg injury | 31 Jul 2026 · 93 days | Early November 2026 |
| Drew Baiera · DEF | injured | Leg injury | 18 Apr 2026 · 197 days | Early November 2026 |
| Kai Trewin · MID | injured | Leg injury | 22 Jul 2026 · 102 days | Late October 2026 |
| Maxi Moralez · MID | injured | Knock | 5 Sept 2026 · 57 days | Late October 2026 |
Orlando City
| Player | Status | Type | Out since | Expected back |
|---|
| Griffin Dorsey · DEF | injured | Back injury | 19 Sept 2026 · 43 days | Unknown |
| Robin Jansson · DEF | injured | Foot injury | 17 Oct 2026 · 15 days | Late November 2026 |
| Tyrese Spicer · FWD | injured | Foot injury | 11 Oct 2026 · 21 days | Mid November 2026 |
Portland Timbers
| Player | Status | Type | Out since | Expected back |
|---|
| Alex Bonetig · DEF | injured | Shoulder injury | 11 Oct 2026 · 21 days | Late November 2026 |
| Brandon Bye · DEF | injured | Leg injury | 29 Aug 2026 · 64 days | Late October 2026 |
| Juan Mosquera · DEF | injured | Foot injury | 11 Apr 2026 · 204 days | Late October 2026 |
| Trey Muse · GK | injured | Concussion | 27 Oct 2026 · 5 days | Late November 2026 |
| Zac McGraw · DEF | injured | Back injury | 19 Sept 2026 · 43 days | Late October 2026 |
Puebla
| Player | Status | Type | Out since | Expected back |
|---|
| Eduardo Navarro · DEF | injured | Physical discomfort | 12 Aug 2026 · 81 days | Doubtful |
| Sergio Sanabria · MID | injured | Muscle injury | 8 Oct 2026 · 24 days | Doubtful |
Pumas
| Player | Status | Type | Out since | Expected back |
|---|
| Cristian Calderón · DEF | injured | Knock | 10 Sept 2026 · 52 days | Doubtful |
| José Macías · MID | injured | Knee injury | 9 Nov 2025 · 357 days | Early November 2026 |
| Sebastián Córdova · FWD | injured | Cruciate ligament injury | 8 Aug 2026 · 85 days | Late April 2027 |
Real Salt Lake
| Player | Status | Type | Out since | Expected back |
|---|
| Diego Luna · MID | injured | Knee injury | 19 Sept 2026 · 43 days | Mid November 2026 |
| Emeka Eneli · FWD | injured | Knee injury | 11 Oct 2026 · 21 days | Early November 2026 |
| Juan José Arias · DEF | injured | Hamstring injury | 19 Sept 2026 · 43 days | Doubtful |
| Lukas Engel · DEF | injured | Hamstring injury | 19 Sept 2026 · 43 days | Doubtful |
Santos Laguna
| Player | Status | Type | Out since | Expected back |
|---|
| Bruno Amione · DEF | injured | Cruciate ligament injury | 12 Jul 2026 · 112 days | Early January 2027 |
| Diego González · MID | injured | Ankle injury | 25 Oct 2026 · 7 days | Early November 2026 |
| Efraín Orona · DEF | injured | Hamstring injury | 25 Oct 2026 · 7 days | Late November 2026 |
| Lucas Di Yorio · FWD | injured | Broken leg | 12 Aug 2026 · 81 days | Early January 2027 |
Tigres
| Player | Status | Type | Out since | Expected back |
|---|
| Francisco Reyes · DEF | injured | Achilles tendon injury | 2 Sept 2026 · 60 days | Early January 2027 |
| Jesús Angulo · DEF | injured | Knee injury | 12 Jul 2026 · 112 days | Mid November 2026 |
| Joaquim · DEF | injured | Muscle injury | 20 Oct 2026 · 12 days | Doubtful |
| Marcelo Flores · FWD | injured | Injured | 31 May 2026 · 154 days | Unknown |
| Marco Farfán · DEF | injured | Muscle injury | 16 Jul 2026 · 108 days | Doubtful |
| Osvaldo Rodríguez · DEF | injured | Knee injury | 7 May 2026 · 178 days | Doubtful |
| Rômulo · DEF | injured | Calf injury | 27 Sept 2026 · 35 days | Doubtful |
Toluca
| Player | Status | Type | Out since | Expected back |
|---|
| Iván López · FWD | injured | Injured | 21 Aug 2026 · 72 days | Unknown |
| Marcel Ruiz · MID | injured | Knee injury | 12 Jul 2026 · 112 days | Early November 2026 |
Vancouver Whitecaps
| Player | Status | Type | Out since | Expected back |
|---|
| Andrés Cubas · MID | injured | Ankle injury | 27 Oct 2026 · 5 days | Late November 2026 |
| Belal Halbouni · DEF | injured | Knee injury | 28 Feb 2026 · 246 days | Unknown |
| Emmanuel Sabbi · FWD | injured | Knock | 26 Oct 2026 · 6 days | Mid November 2026 |
| Kenji Cabrera · FWD | injured | Foot injury | 16 Jul 2026 · 108 days | Late October 2026 |
| Sam Adekugbe · DEF | injured | Hamstring injury | 11 Oct 2026 · 21 days | Early November 2026 |
Injury type and out-since come from the daily squad feed; a blank type means the provider reported an injury without a category. Expected returns are the provider’s own wording.
Atlético de San Luis
Columbus Crew
FC Cincinnati
FC Dallas
Inter Miami CF
Los Angeles FC
Monterrey
Nashville SC
Pachuca
Philadelphia Union
Querétaro FC
San Diego FC
Seattle Sounders FC
Tijuana